Full-Time Bioinformatics Developer
Job Description
The Ensembl Project, based at the European Bioinformatics Institute (EMBL-EBI), develops free, comprehensive genome data services for a worldwide audience, distributing gene and genome data through an online genome browser and publicly accessible databases and APIs. We seek a highly motivated, talented, and experienced Bioinformatics Developer to contribute to our variation and phenotype resources.
In the Ensembl Variation team, we build workflows for the aggregation and annotation of large-scale data from public archives. We develop tools for data access, visualisation, and variant interpretation, including the widely-used Ensembl Variant Effect Predictor (VEP). Improvements in sequencing technology and the development of novel techniques are generating new data types and ever larger datasets. These data need efficient management and intuitive presentation to reach their full scientific potential, improving our understanding of genetic disease, evolution, and population genetics. We collaborate with clinical research scientists, genomics researchers, and standards-setting communities to help guide development of our services.
Your role
Your primary responsibilities will include:
- Developing and maintaining tools for the functional annotation and prioritisation of genomics variants, including Ensembl VEP.
- Developing, maintaining, and running efficient methods for management of/access to large-scale variation data for community use and to power the Ensembl websites.
- Investigating and integrating new sources of genomic variation, phenotype association data, and prediction tools.
- Collaborating with members of the wider Ensembl team both on specific development projects and to coordinate regular data and software releases.
- Liaising with other groups at EMBL-EBI and external collaborators to add new functionalities to our tools and agree on community standards for data representation.
- Supporting our users and presenting our work at internal meetings and scientific conferences.
This position offers a motivated candidate an exciting opportunity to contribute to highly-used open-source bioinformatics resources and to develop domain knowledge in a fast-moving scientific area. You will work closely with a team of bioinformaticians and developers and interact with other groups at the EMBL-EBI and beyond.
You have
- Experience in the design and development of user-friendly software or code, with proficiency in Python.
- Experience of managing and analysing large-scale genomics data, preferably genetic variation data.
- Experience working with large-scale relational databases, preferably MySQL.
- Proficiency working in a UNIX/Linux environment.
- Excellent attention to detail and the ability to deliver a high-quality product to agreed deadlines.
- Good communication and interpersonal skills.
- Scientific curiosity and initiative.
You might also have
- Familiarity with the Ensembl resources, in particular Ensembl VEP.
- Experience working in a HPC bioinformatics environment, ideally creating and managing efficient large-scale data analysis pipelines using NextFlow.
- Experience collaborating on projects, working with colleagues from different disciplines, and using version control platforms, ideally GitHub.
- Design and development of REST or GraphQL APIs.
- Experience with a range of bioinformatics or statistical tools and data formats.
- Familiarity with another programming language such as Perl and/or C.
Apply now! Benefits and Contract Information
- Financial incentives: depending on circumstances, monthly family/marriage allowance of £272 monthly child allowance of £328 per child. Non resident allowance up to £556 per month. Annual salary review, pension scheme, death benefit, long-term care, accident-at-work and unemployment insurances
- Hybrid working arrangements
- Private medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover)
- Generous time off: 30 days annual leave per year, in addition to eight bank holidays
- Relocation package including installation grant (as applicable)
- Campus life: Free shuttle bus to and from work, on-site library, subsidised on-site gym and cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely)
- Family benefits: On-site nursery, child sick leave, generous parental leave, holiday clubs on campus and monthly family and child allowances
- Contract duration: This position is a 2 year project based contract
- Salary: Monthly salary starting at £3,229 after tax but excl. pension & insurances) + benefits (Total package will be dependent on family circumstances)
- International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants.
- Diversity and inclusion: At EMBL-EBI, we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women, LGBTQ+ and individuals from all nationalities.
- Job location: This role is based in Hinxton, near Cambridge, UK. You will be required to relocate if you are based overseas and you will receive a generous relocation package to support you.
How to Apply
To apply, please submit a covering letter and CV via our online system. Applications will close on 18/08/2024. https://www.embl.org/jobs/position/EBI02276117 total views, 0 today