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20 Dec 2020

Full-Time Vector Purification and Formulation Lead

UCB Bioscience – Posted by UCBdenise Boston, Massachusetts, United States

Job Description

To strengthen our Early Solutions and External Innovation team, based in our Boston Office in Bedford, MA, we are looking for a talented individual to fill the position of: Vector Purification and Formulation Lead.

As a Vector Purification and Formulation Lead you will support multiple therapeutic gene therapy programs by leading AAV vector purification and formulation for use in research and initial process development.

You will contribute by:

  • Purification of viral vectors (AAV) – benchtop to 50L bioreactor scale
  • Establish and optimize downstream processes for multiple programs
  • Establish automation capability across entire gene therapy purification operations
  • Responsible for purification schedule, filtration & chromatography unit operations
  • Hands-on technical leadership and managerial responsibility for downstream and formulation research team
  • Collaborate with upstream, analytics and vector biology teams within Gene Therapy Vector Core and Discovery, Tox and CMC teams within the greater organization
  • Ability to function independently and cross functionally across various UCB teams (medicinal chemists, cell biologists, disease area exerts, antibody engineers, etc)
  • Ability to manage priorities, and engage/communicate in a multidisciplinary environment

Interested? For this position you’ll need the following education, experience and skills:

     Minimum Qualifications:

  • Ph.D in a related science or field
  • A minimum of 3 years of viral vector purification and formulation experience in industry

Preferred Qualifications:

  • Biologics downstream process development and tech transfer experience in industry is a plus.
  • IND and BLA filing experience for gene therapy applications is a plus.


Why you should apply

At UCB, we strive to attract passionate and outstanding talents who thrive on change and are ready to bring real value to patients. Working for us you’ll discover a place where you can grow and express your full potential. We place an emphasis on innovation, collaboration and impact. Through meaningful recognition and a motivating work atmosphere, we aim to provide an optimal experience by caring about and valuing our employees – just as we do for the patients we serve.


If you believe you are the perfect match to join us on our pioneering adventure, then we invite you to apply and tell us more about your profile and motivation.


About Us

At UCB, we come together every day to work, laser-focused, on a simple question: How will this create value for people living with severe diseases? By putting patients at the heart of everything we do, our approach – from discovery to development to delivery – is continuously transformed and designed around patient needs and their journey.

With a team of approximately 7,500 employees worldwide operations in more than 40 countries, we are a global biopharmaceutical company investing more than a quarter of our revenue in cutting-edge scientific research. We are focused on addressing chronic, neurological, immunological, and bone diseases. We are looking for people with passion and empathy who develop a real understanding of patient’s needs and can deliver thoughtful solutions to decisionmakers across the heath care ecosystem.

Curious to know more? Please visit our website

How to Apply

Job Categories: Equal Opportunities. Job Types: Full-Time. Salaries: Not Disclosed.

Job expires in 57 days.

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