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28 Apr 2021

Full-Time Translational Bioinformatics Lead

UCB Pharma – Posted by UCBdenise Boston, Massachusetts, United States

Job Description

Help us transform patients’ lives.

At UCB, we put our heart, soul and skills into making a difference for people living with significant unmet needs. Working together, we blend the best of our talents to deliver thoughtful solutions that patients value. Will you join us in this pioneering adventure?


UCB leverages an innovative macrocyclic drug peptide platform to develop best-in-class investigational treatments for complement mediated diseases. As a Translational Bioinformatics Lead on the Translational Bioinformatics team, you will provide computational biology expertise to affect translational decision making at all stages of drug discovery and development, through the integrative analysis and biological interpretation of complex, poly-omic data sets.

In this role you will ally advanced analytical capabilities and biological domain understanding to reveal mechanistic insight into disease and drug action. Working in multi-disciplinary, translational teams as a subject matter expert to help guide the design of omic studies. Leveraging scalable, cloud environments to efficiently develop and execute processing pipelines, as well as conduct and communicate exploratory, functional analyses.

The role will be supported by an international team of experienced and committed bioinformatics scientists.

You will contribute by:
•    Gaining insight into target mechanisms and disease aetiology through analysis and interpretation of poly-omic data from patient samples, and in vitro and ex vivo model systems.
•    Leading the development and creation of a local bioinformatic capability at UCB in Boston, including the establishment of supporting infrastructure to manage high-dimensional biological data sets and enable the development of scalable processing and analytical workflows.
•    Acting as subject matter expert collaborating with multi-disciplinary project teams, to design and analyze experiments, and generate insight that materially influences decision making.
•    Driving innovation by applying state of the art tools and technologies and developing novel statistical and AI methodologies.

Interested? For this position, you’ll need the following educationexperience and skills:

Minimum Qualifications:

•    PhD or equivalent education in bioinformatics, computational biology, or data science.
•    3+ years of work experience in a life-science environment.
•    5+ years of demonstrated ability to develop, implement, and proactively apply project-tailored data analysis workflows to answer scientific questions.
•    5+ years of experience in pre-processing, integration and analysis of different omic data types (e.g. gene expression, proteomic, genetic data, etc.).
•    5+ years of experience using methods pertinent for functional interpretation of omics data, such as pathway enrichment, functional module detection, causal reasoning.
•    5+ years of experience using advanced computational skills, such as experience of operating in a HPC Unix environment, cloud-based computational and/or pipelining platforms, and proficiency in a range of programming languages common to the bioinformatics community such as Python or R.

Preferred Qualifications:

•    Familiarity with advanced statistical and machine learning methods as well as bespoke strategies for integrative analysis of multiple omic data types
•    Ability to interpret and communicate effectively the outcomes of analytical work to a non-expert audience in order to trigger efficient decision-making.

Why you should apply:

Do you want to contribute in bringing real value to patients living with severe diseases while driving innovation forward?

Join UCB’s dynamic, inspiring and innovative environment. You will be recognized for impactful performance via a competitive compensation and benefits package and you will enjoy ample personal development opportunities.

Tell us what makes you the perfect match to our team and join one of the most dynamic & forward-looking organizations in the world.
To apply, please go to

About Us

At UCB, we come together every day to work, laser-focused, on a simple question: How will this create value for people living with severe diseases? By putting patients at the heart of everything we do, our approach – from discovery to development to delivery – is continuously transformed and designed around patient needs and their journey.

With a team of approximately 7,500 employees worldwide operations in more than 40 countries, we are a global biopharmaceutical company investing more than a quarter of our revenue in cutting-edge scientific research. We are focused on addressing chronic, neurological, immunological, and bone diseases. We are looking for people with passion and empathy who develop a real understanding of patient’s needs and can deliver thoughtful solutions to decisionmakers across the heath care ecosystem.

Curious to know more? Please visit our website

How to Apply

Job Types: Full-Time.

Job expires in 77 days.

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