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13 Jun 2022

Full-Time Senior Scientist (Organic Chemistry)

Ultima Genomics – Posted by Ultima Genomics Newark, California, United States

Job Description

Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. We have developed a foundational new approach to sequencing at scale that overcomes limitations due to the high costs of current technologies. We are well-funded and have raised approximately $600 million from global top-tier investors. Our team brings together unique and diverse expertise across multiple disciplines, from healthcare and life sciences, to engineering, to technology and software and beyond. We are a collaborative group of more than 350 employees, including successful entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, molecular and computational biologists, software and algorithm experts, and operations and commercial leaders. Join us to develop and commercialize technologies that unleash the power of genomics at scale and empower the future of human health.

We are looking for a highly motivated Senior Scientist to join our team!

The successful candidate will play a key role in the development of our company’s core chemistry. The candidate combines a strong synthetic chemistry background, understanding of analytical methods and instrument operation, interpretation of analytical data, and responsibility for delivering robust and scalable synthesis workflows.

How You’ll Contribute

  • Plan and execute laboratory experiments involving: organic synthesis, compound characterization, and scale-up of modified nucleotides and fluorescent dye conjugates
  • Documentation of experimental details, structural determination (NMR, MS) of novel compounds, analysis and interpretation of data, and presentation of results
  • Assist in the preparation of patents and publications to increase the company’s intellectual property portfolio
  • Operation and maintenance of state-of-the-art laboratory equipment & analytical instruments
  • Collaborate with a wide spectrum of scientists & engineers on joint projects, and support R&D
  • Actively participate in the company’s quality and safety programs, and adhere to policies and procedures to maintain compliance with all federal, state and local regulations.

Qualifications, Skills, Knowledge & Abilities

  • Ph.D. with 0 – 8 years of industry experience in chemistry or organic chemistry
  • Proven track record in carrying out multi-step organic synthesis, purification, and characterization of novel organic compounds
  • Strong understanding of organic reaction mechanisms, and the ability to optimize reaction conditions based on this knowledge
  • Experience with flash chromatography and analytical methods including MS, TLC, and UV
  • Experience with oxygen/moisture sensitive reactions that require inert, dry, low temperature conditions such as organolithium, organomagnesium, and transition metal catalyzed chemistry
  • Excellent communication, organizational, and people skills are a must, as well as reliability and time management abilities
  • Demonstrated ability to plan and execute independent and collaborative research projects
  • Strong sense of urgency, can-do attitude, and motivational skills to get the best out of the co-workers.
  • Co-authorship in one or more publications in peer-reviewed scientific journal(s).
  • In-depth understanding and hands-on experience with preparative-LC (reverse phase or ion exchange chromatography) methods are preferred
  • Ability to conduct reactions at both medicinal chemistry scale (~50 mg) and at low process scale (~200 g) is preferred
  • Proficient with SciFinder, Chemdraw, Mnova, and/or other chemistry-related software is preferred
  • Experience in managing external CROs and the sourcing of related raw materials and intermediates is preferred

We provide equal employment opportunity for all applicants and employees. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), gender identity, gender expression, national origin, ancestry, citizenship, age, physical or mental disability, military or veteran status, marital status, domestic partner status, sexual orientation, genetic information, or any other basis protected by applicable laws.

 

 

Job Categories: Equal Opportunities. Job Types: Full-Time. Job Tags: 522.

Job expires in 73 days.

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